Disease: Immune thrombocytopenic purpura
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ZAP70 P43403 zeta chain of T cell receptor associated protein kinase 70 Kinase 0.88 0.497 0.769
TRIM21 P19474 tripartite motif containing 21 3.4E-09 0.485 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
SUB1 P53999 SUB1 regulator of transcription 0.89 0.465 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
STAT1 P42224 signal transducer and activator of transcription 1 Nucleic acid binding 1.00 0.399 0.885
RFXAP O00287 regulatory factor X associated protein 2.3E-02 0.663 0.577
RFXANK O14593 regulatory factor X associated ankyrin containing protein Transcription factor 8.7E-06 0.644 0.577
RFX5 P48382 regulatory factor X5 Enzyme 2.0E-11 0.650 0.577
RBM45 Q8IUH3 RNA binding motif protein 45 2.1E-10 0.383 0.846
PTPN22 Q9Y2R2 protein tyrosine phosphatase non-receptor type 22 3.5E-21 0.438 0.846
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
PDCD1 Q15116 programmed cell death 1 0.42 0.402 0.846
NXT1 Q9UKK6 nuclear transport factor 2 like export factor 1 0.65 0.505 0.731
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
MRPL28 Q13084 mitochondrial ribosomal protein L28 2.0E-07 0.505 0.731
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MIR146A microRNA 146a 0.398 0.885
MIF P14174 macrophage migration inhibitory factor 1.2E-02 0.412 0.885
LGALS9 O00182 galectin 9 Signaling 6.5E-06 0.496 0.769
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
IL9 P15248 interleukin 9 8.1E-07 0.461 0.846